Febuxostat impurity 8 E1 ACT 335827 is a potent

ACT 335827 is a potent and selective antagonist of OXR-1 with IC50 values of 120 and 2300 nM for OXR-1 and OXR-2

whereas KP136 shows an overt inhibitory effect of about 66% at the oral dose of 2 mg/kg

preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the central nervous system (CNS)

8 µM against PC-3 cells compared with the parent compound LQZ-7

Neobavaisoflavone (1-100 μM

Febuxostat impurity 8 E1 ACT 335827 is a potentFebuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0. 6 nM. Product information CAS Number: 144060 62 8 Molecular Weight: 319. 38 Formula: C16H17NO4S Chemical Name: 2 [3 formyl 4 (2 methylpropoxy)phenyl] 4 methyl 1,3 thiazole 5 carboxylic acid Smiles: CC1N=C(SC=1C(O)=O)C1=CC(C=O)=C(C=C1)OCC(C)C InChiKey: OHIQHHXCAMMCPH UHFFFAOYSA N InChi: InChI=1S C16H17NO4S c1 9(2)8 21 13 5 4 11(6