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InChiKey: RSKMQDIAPGOWDL-UHFFFAOYSA-N
43(6):1334-9
with an EC50 of 19 nM for hM4
stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB)
The intravenous (IV) administration of the formulation to mice bearing 4T1 breast cancer tumors results in nanoparticle accumulation in tumors
Hydrocortisone hemisuccinate 414KF-82958 hydrobromide InChiKey: RSKMQDIAPGOWDL-UHFFFAOYSA-NHydrocortisone hemisuccinate (Hydrocortisone 21 hemisuccinate), a physiological glucocorticoid, is an orally active steroidal anti inammatory drug (SAID). Hydrocortisone hemisuccinate inhibits proinflammatory cytokine activity, with IC50s of 6. 7 and 21. 4 M for IL 6 and IL 3, respectively. Hydrocortisone hemisuccinate can be used for the research of ulcerative colitis (UC). Product information CAS Number: 2203 97 6 Molecular Weight: 462. 53 Formula:
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