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InChi: InChI=1S/C19H23N3O7/c20-5-6-27-7-8-28-9-10-29-12-1-2-13-14(11-12)19(26)22(18(13)25)15-3-4-16(23)21-17(15)24/h1-2
KRN633 might be useful in the treatment of solid tumors and other diseases that depend on pathologic angiogenesis
is a potent and selective WD repeat-containing protein 5 (WDR5) antagonist with Kd of 450 nM
but not those lacking BLM
Meneghin E
Thalidomide-PEG3-COOH Size:Contact [email protected] for quotation InChi: InChI=1S/C19H23N3O7/c20-5-6-27-7-8-28-9-10-29-12-1-2-13-14(11-12)19(26)22(18(13)25)15-3-4-16(23)21-17(15)24/h1-2Thalidomide PEG3 COOH is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Product information Molecular Weight: 434. 40 Formula: C20H22N2O9 Chemical Name: 3 [2 (2 {[2 (2, 6 dioxopiperidin 3 yl) 1, 3 dioxo 2, 3 dihydro 1H isoindol 5 yl]oxy}ethoxy)ethoxy]propanoic acid Smiles: OC(=O)CCOCCOCCOC1=CC2=C(C=C1)C(=O)N(C1CCC(=O)NC1=O)C2=O InChiKey: PZDWKEFNXUZNPV
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