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cell penetrating calpain inhibitor
Rajkumar SV
3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)-acetamide
DGAT1-IN-3 blocks the human ether-a-go-go-related gene (hERG) encoded potassium channel with an IC20 of 0
UNII-LXU5241LCL
Pexidartinib G4-Amine cell penetrating calpain inhibitorPexidartinib (PLX 3397) is a potent, orally active, selective, and ATP competitive colony stimulating factor 1 receptor (CSF1R or M CSFR) and c Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX 3397) exhibits 10 to 100 fold selectivity for c Kit and CSF1R over other related kinases. Pexidartinib (PLX 3397) induces cell apoptosis and has anti tumor activity. Product information CAS Number: 1029044 16 3 Molecular Weight: 417. 81
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