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NS(=O)(=O)C1=CC(C(O)=O)=C(C=C1Cl)NCC1=CC=CO1 |^1:0|
InChi: InChI=1S/C40H78N14O8/c1-25(2)32(39(61)62)54-38(60)30(16-6-10-22-44)52-37(59)31(18-12-24-48-40(45)46)53-36(58)29(15-5-9-21-43)51-35(57)28(14-4-8-20-42)50-34(56)27(13-3-7-19-41)49-33(55)26-17-11-23-47-26/h25-32
Spasojevic I
9)10/h11-12
point mutations of which significantly obstruct fibril formation and have been used to generate inhibitors of fibrillogenesis
MELK-IN-1 Size:Contact [email protected] for quotation NS(=O)(=O)C1=CC(C(O)=O)=C(C=C1Cl)NCC1=CC=CO1 |^1:0|MELK IN 1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 and a Ki of 3 nM and 0. 39 nM, respectively. Product information CAS Number: 2095596 44 2 Molecular Weight: 539. 62 Formula: C31H33N5O4 Chemical Name: methyl 2 hydroxy 3 [({4 [N methyl 2 (4 methylpiperazin 1 yl)acetamido]phenyl}imino)(phenyl)methyl] 1H indole 5 carboxylate Smiles:
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