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Crizotinib inhibits the membrane receptor MET and activation of the MET signaling pathway
CAS Number: 189453-10-9
Isopentyl 4-methoxycinnamate
C4H6O4/c1-17(20-14-13-19(2)3
C[C@@](O)([C@H](CC([O-])=O)C([O-])=O)C([O-])=O
Regorafenib Catalog No.:M10913-10 Crizotinib inhibits the membrane receptorRegorafenib, also known as BAY 73 4506 ; is a n orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. Regorafenib demonstrated to increase the overall survival of patients with metastatic