Pizotifen Malate n (trihydrate) 6 µM confirming the inhibition

6 µM confirming the inhibition of NMDA receptors observed in electrophysiological experiments

InChiKey: LLXISKGBWFTGEI-FQEVSTJZSA-N

Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors

is highly potent and selective mutant JAK2 (V617F) inhibitor with an IC50 of ~55 nM

1996 Jan 5

Pizotifen Malate n (trihydrate) 6 µM confirming the inhibitionPizotifen, also known as Pizotyline, is a benzocycloheptene based drug used as a medicine, primarily as a preventative to reduce the frequency of recurrent migraine headaches. Pizotifen is a serotonin antagonist acting mainly at the 5 HT2A and 5HT2C receptors. It also has some activity as an antihistamine as well as some anticholinergic activity. Product information CAS Number: 5189 11 7 Molecular Weight: 429. 53 Formula: C23H27NO5S Synonym: