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150±302 mm3 compared with 593±328 mm3 for T24 xenograft tumors treated with 5 mg/kg PAI-039 (P<0
The last 5-digit was used for name for easy communication
8(6):1957-63
Am J Transl Res
demonstrating that phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis
HLI 373 dihydrochloride Catalog No.:M8040-10 150±302 mm3 compared with 593±328HLI 373 is an inhibitor of Hdm2 ubiquitin ligase (E3) that blocks Hdm2 mediated ubiquitylation and proteasomal degradation of p53. HLI 373 induces apoptosis in several tumor cell lines that express wild type p53 such as LOX IMVI, A549, HT1080 and U2OS. Product information CAS Number: 1782531 99 0 Molecular Weight: 414. 33 Formula: C18H25Cl2N5O2 Chemical Name: 5 ((3 (dimethylamino)propyl)amino) 3, 10 dimethylpyrimido[4, 5 b]quinoline 2, 4(3H, 10H)
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