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It inhibits the conjugation of Ub to a range of E2 enzymes and inhibits E2 enzyme mediated IκBα phosphorylation and indirectly decreases NF-κb activity
also known as HAUSP
its expression in tumors is associated with a more aggressive phenotype
33)9-27-15-30-14(11-4-3-5-12(29-11)18(20
may be a useful agent for the study of AhR-mediated signal transduction and the prevention of TCDD-associated pathology
SU-5402 - FGFR inhibitor. CAS# 215543-92-3 size:2mg solid It inhibits the conjugation ofSU 5402, CAS No. 215543 92 3, is a potent inhibitor of FGFR, VEGFR, and PDGFR. SU 5402 has been used in many studies to inhibit cancer cell growth, or modulate stem cell phenotypes, including maintenance of mouse ESCs, or inducing generation of functional human nociceptors from human ESCs iPSCs when combined with LDN193189 BMP inhibitor, SB431542 TGF inhibitor, CHIR99021 GSK3 inhibitor, and DAPT Notch inhibitor. Product information CAS Number: 215543