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PF-4840154 ydroxy-2-naphthoic acid InChiKey: PQSUYGKTWSAVDQ-ZVIOFETBSA-N

SKU: 46916585382

4.6
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Description

InChiKey: PQSUYGKTWSAVDQ-ZVIOFETBSA-N

Overcoming the resistance to crizotinib in patients with non-small cell lung cancer harboring EML4/ALK translocation

4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against FL NS3/4a

The corresponding residues of Her-2

Proteasome inhibitor IX (AM114) exhibits potent activity against p53+/+ cells in colony formation assay

PF-4840154 ydroxy-2-naphthoic acid InChiKey: PQSUYGKTWSAVDQ-ZVIOFETBSA-NPF 4840154 is a potent, selective agonist of the rat and human TrpA1 channel with EC50s of 97 and 23 nM, respectively. PF 4840154 elicits TrpA1 mediated nocifensive behaviour in mouse. Product information CAS Number: 1332708 14 1 Molecular Weight: 466. 62 Formula: C26H38N6O2 Chemical Name: N benzyl 4 [(2 methylpropyl)amino] 2 {4 [(oxan 3 yl)methyl]piperazin 1 yl}pyrimidine 5 carboxamide Smiles: CC(C)CNC1=NC(=NC=C1C(=O)NCC1=CC=CC=C1)N1CCN(CC2COCCC2)CC1

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