SAICAR Size:Contact [email protected] for quotation 4-oxadiazol-2-yl}-3-carbamoylpropyl]carbamoyl}amino)-3-hydroxypropanoic acid

4-oxadiazol-2-yl}-3-carbamoylpropyl]carbamoyl}amino)-3-hydroxypropanoic acid

The IC50 of NSC745885 is 0

mediated via JAK2)

It is less toxic by binding to Hsp90 and altering its function

Chemical Name: 7-chloro-N-[6-({6-[(7-chloroquinolin-4-yl)amino]hexyl}(methyl)amino)hexyl]quinolin-4-amine

SAICAR Size:Contact [email protected] for quotation 4-oxadiazol-2-yl}-3-carbamoylpropyl]carbamoyl}amino)-3-hydroxypropanoic acidSAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme selective manner, with an EC50 of 0. 3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose limited conditions. Product information CAS Number: 3031 95 6 Molecular Weight: 454. 28 Formula: C13H19N4O12P Chemical Name: (2S) 2 ({5 amino 1 [(2R,3R,4S,5R) 3,4 dihydroxy 5 [(phosphonooxy)methyl]oxolan 2 yl] 1H