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Acnefree Adapalene Gel Once Daily Topical Retinoid Acne Treatment, 0.5 Oz Google Ads Hidden 2 Rinse thoroughly to prevent anyDescription AcneFree Adapalene Gel 0. 1% is a once daily topical retinoid acne treatment that provides prescription strength results without a prescription. This 0. 5 ounce tube contains adapalene, a third generation retinoid that works deep in pores to prevent acne formation and promote skin cell turnover. Clinically proven to reduce acne lesions and prevent new breakouts, this treatment is suitable for teens and adults with mild to moderate acne.