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Continued evaluation of treated mice on termination of treatment shows no resumption of tumor growth
Oral dosing with EPZ015666 demonstrated dose-dependent antitumor activity in multiple MCL xenograft models
Epub 2012 Sep 11
e110180 (2014)
GKT-137831
BMS-5 - CAS# 1338247-35-0 size:10mg solid Continued evaluation of treated miceBMS 5, a Potent LIM kinase inhibitor., CAS No. 1338247 35 0, is a Potent LIM kinase inhibitor (IC50 values are 7 and 8 nM for LIMK1 and LIMK2 respectively). Inhibits cofilin phosphorylation in MDA MB 231 breast cancer cells. Reduces MDA MB 231 tumor cell invasion in a 3D matrigel invasion assay. Product information CAS Number: 1338247 35 0 Molecular Weight: 431. 29 Formula: C17H14Cl2F2N4OS Synonym: LIMKI 3 LIMKI 3 LIMKI3 BMS 5 BMS 5 BMS5 Chemical
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