PHD-1-IN-1 sulfosuccinimide sodium PI4KIIIbeta-IN-9 (Compound 9) forms a

PI4KIIIbeta-IN-9 (Compound 9) forms a crescent shape that conforms to the active site of PI4KIIIβ

GSK-3β inhibitor 3 (compound 4-3) (100 μM) inhibits GSK-3α activity by 87

and a pKd of 9

2016 Dec 5

estrogenic

PHD-1-IN-1 sulfosuccinimide sodium PI4KIIIbeta-IN-9 (Compound 9) forms aPHD 1 IN 1 is an orally active and potent HIF prolylhydroxylase domain 1 (PHD 1) inhibitor with an IC50 of 0. 034 M. PHD 1 IN 1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an Arg367 out pocket. Product information CAS Number: 2009343 14 8 Molecular Weight: 220. 23 Formula: C13H8N4 Chemical Name: 4 {[1,2,4]triazolo[1,5 a]pyridin 5 yl}benzonitrile Smiles: N#CC1C=CC(=CC=1)C1=CC=CC2=NC=NN21