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PERK-IN-2 DMT-N4-Bz-2'-F-dC AZD9272 causes no cocaine-appropriate responding

SKU: 41399783358

4.2
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Description

AZD9272 causes no cocaine-appropriate responding and causes a non-dose-dependent reduction in response rates at higher doses

65 mg/kg in the Icilin-induced wet-dog shakes model in rats after oral administration

InChiKey: TXLSDIXNZRLFCH-ZRDCEPLESA-N

Schwartzman ML

Inhibition of adenosine kinase can selectively enhance the protective actions of adenosine during tissue trauma without producing the nonspecific effects associated with the systemic administration of adenosine receptor agonists

PERK-IN-2 DMT-N4-Bz-2'-F-dC AZD9272 causes no cocaine-appropriate respondingPERK IN 2 is a potent PERK inhibitor with an IC50 of 0. 2 nM. Product information CAS Number: 1337531 83 5 Molecular Weight: 437. 42 Formula: C23H18F3N5O Chemical Name: 1 (5 {4 amino 7 methyl 7H pyrrolo[2,3 d]pyrimidin 5 yl} 2,3 dihydro 1H indol 1 yl) 2 (2,3,5 trifluorophenyl)ethan 1 one Smiles: CN1C=C(C2=C(N)N=CN=C12)C1=CC=C2C(CCN2C(=O)CC2=CC(F)=CC(F)=C2F)=C1 InChiKey: JCUSVFKWUQBVHH UHFFFAOYSA N InChi: InChI=1S C23H18F3N5O c1 30 10 16(20 22(27)28 11

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