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O-Desmethyl gefitinib - CAS# 847949-49-9 182AM7 E 195514-80-8

SKU: 41274225427

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Description

195514-80-8

Chemical Name: 1-(4-(4-(8-oxa-3-azabicyclo[3

which blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma

Chemical Name: 5-((3-chlorophenyl)amino)benzo[c][2

InChi: InChI=1S/C27H29ClN6O2/c1-19-25(18-30-34(19)24-5-2-21(28)3-6-24)27(35)31-22-4-7-26(20(16-22)17-29)33-10-8-23(9-11-33)32-12-14-36-15-13-32/h2-7

O-Desmethyl gefitinib - CAS# 847949-49-9 182AM7 E 195514-80-8O Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O desmethyl gefitinib is dependent on CYP2D6 activity. O desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays. Product information CAS Number: 847949 49 9 Molecular Weight: 432. 88 Formula: C21H22ClFN4O3 Chemical Name: 4 [(3 chloro 4 fluorophenyl)amino] 6 [3 (morpholin 4 yl)propoxy]quinazolin 7 ol Smiles:

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