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In vitro: WWL123 was identified as a brain-penetrant inhibitor of ABHD6 demonstrating over 10-fold selectivity for ABHD6 compared to a panel of about 35 other serine hydrolases
Replacement of the sn-2 oxygen in the glycerol moiety of 2-AG with a nitrogen atom produces Arachidonoyl Serinol
Formula: C47H56N10O11
Ro 31-8220 inhibits release of interleukin-1 and interleukin-6 from mouse peritoneal macrophages induced by fibrin fibrinogen degradation products
3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
AI-3 0739 In vitro: WWL123 was identifiedProduct information CAS Number: 882288 28 0 Molecular Weight: 292. 80 Formula: C11H13ClO3S2 Chemical Name: 1 chloro 3 methanesulfonyl 6,6 dimethyl 4,5,6,7 tetrahydro 2 benzothiophen 4 one Smiles: CC1(C)CC(=O)C2C(C1)=C(Cl)SC=2S(C)(=O)=O InChiKey: PVJWSALSWFDIMS UHFFFAOYSA N InChi: InChI=1S C11H13ClO3S2 c1 11(2)4 6 8(7(13)5 11)10(16 9(6)12)17(3,14)15 h4 5H2,1 3H3 Technical Data Appearance: Solid Power Purity: 98% (or refer to the Certificate of
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