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IV pharmacokinetics are characterized by moderate clearance in rat and low clearance in dog
the IC50 values are 85 and 63 nM
InChiKey: IWBOPFCKHIJFMS-UHFFFAOYSA-N
Formula: C10H14N5O8P
Patamostat mesylate potently inhibits trypsin
TD52 - CAS# 1798328-24-1 4363 IV pharmacokinetics are characterized byTD52, an Erlotinib (HY 50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 mediates the apoptotic effect in triple negative breast cancer (TNBC) cells via regulating the CIP2A PP2A p Akt signalling pathway. TD52 indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 has less p EGFR inhibition and has potent anti cancer activity. Product information CAS Number: