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L-NIL has approximately 6-fold greater potency for miNOS than either L-NMA or L-NNA
Smiles: CN(C)[C@@H](C)C1=CC(=CC=C1)OC(=O)N(C)CC
InChi: InChI=1S/C27H26F3NO3/c1-18-20(9-6-10-23(18)21-7-4-3-5-8-21)12-13-22-15-19(11-14-24(22)27(28
InChiKey: NZYOAGBNMCVQIV-UHFFFAOYSA-N
3-dihydro-1H-isoindol-2-yl)propyl]dimethylazaniumyl}hexyl)dimethylazanium dibromide
Apremilast D5 18274 L-NIL has approximately 6-fold greaterApremilast D5 (CC 10004 D5) is a deuterium labeled Apremilast. Apremilast is an orally available inhibitor of type 4 cyclic nucleotide phosphodiesterase (PDE 4) with an IC50 of 74 nM. Apremilast inhibits TNF release by lipopolysaccharide (LPS) with an IC50 of 104 nM. Product information CAS Number: 1258597 47 5 Molecular Weight: 465. 53 Formula: C22H24N2O7S Chemical Name: N {2 [(1S) 1 {3 [(1,1,2,2,2 H)ethoxy] 4 methoxyphenyl} 2 methanesulfonylethyl]