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SB-267268 inhibits the attachment of bothαvβ3-transfected HEK293 cells to microtiter plate wells precoated with arginine-glycine-aspartic acid (RGD)-containing matrix proteins with IC50 values of 12 nM
Solubility: DMSO : ≥ 30 mg/mL (29
TG101348 was used at 1 µM in vitro
Cariprazine causes a dose-dependent dopamine D2/D3 receptor occupancy of ~45% and ~80% for both antagonist [11C] raclopride and agonist radioligand [11C]MNPA
but there is no regrowth at concentrations of 4×MIC and 8×MIC after 24 h of incubation
DM3-SMe Catalog No.:M18050-C SB-267268 inhibits the attachment ofDM3 SMe is a maytansine derivative and a tubulin inhibitor, and is a cytotoxic moiety of antibody drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM3 SMe shows highly cytotoxic activity in vitro with an IC50 of 0. 0011 nM. Product information CAS Number: 796073 70 6 Molecular Weight: 812. 43 Formula: C38H54ClN3O10S2 Chemical Name: (1S,2R,3S,5S,6S,20R,21S) 11 chloro 21 hydroxy 12,20 dimethoxy