Telotristat ethyl Size:10mg solid 5 mg/kg in a-syn transgenic

5 mg/kg in a-syn transgenic mice

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Telotristat ethyl Size:10mg solid 5 mg/kg in a-syn transgenicTelotristat ethyl, also known as LX 1032 or LX 1606, is an oral serotonin synthesis inhibitor or peripheral tryptophan hydroxylase (TPH) inhibitor . Telotristat etiprate has activity in controlling diarrhea associated with carcinoid syndrome. LX1606 acts by inhibiting the enzyme tryptophan hydoxylase (TPH) and reduces serotonin production both inside and outside the GI tract without affecting brain serotonin levels. TPH is the rate limiting enzyme