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NOW Supplements, L-Tryptophan 500 mg, Encourages Positive Mood*, Supports Relaxation*, 120 Veg Capsules Oxygen Therapy When to use self-heal flowerL Tryptophan is an essential amino acid; therefore, it is not synthesized by the body and must be obtained from the diet. L Tryptophan is critical for the production of serotonin and melatonin, which help to support a positive mood, healthy sleep patterns, and proper immune system function. Every lot of NOW L Tryptophan is tested to be free of Peak E and microbial contamination.