SPR inhibitor 3 J4 hydrochloride of deubiquitinating enzyme (DUB) activity

of deubiquitinating enzyme (DUB) activity

TLR7 agonist 1 is a potent

Smiles: NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CC1C=CC(O)=CC=1

Formula: C26H19N3O5

Formula: C11H14BrClN3O5P

SPR inhibitor 3 J4 hydrochloride of deubiquitinating enzyme (DUB) activitySPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell based assay (IC50=5. 2 M). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels. Product information CAS Number: 1292285 54 1 Molecular Weight: 262. 30 Formula: C14H18N2O3 Chemical