Vinblastine sulfate Size:Solid 2 mg Smiles: CN(C)C1C=CC(=CC=1)C(C1=CC(=CC=C1Cl)[N+]([O-])=O)C1C=CC(=CC=1)N(C)C

Smiles: CN(C)C1C=CC(=CC=1)C(C1=CC(=CC=C1Cl)[N+]([O-])=O)C1C=CC(=CC=1)N(C)C

gov/books/NBK548012/ PubMed PMID: 31643344

exhibits only background levels of caspase-3/7 activity

Indirubin also suppresses the NF-κB activation induced by various inflammatory agents and carcinogens

which is predominantly cleared renally

Vinblastine sulfate Size:Solid 2 mg Smiles: CN(C)C1C=CC(=CC=1)C(C1=CC(=CC=C1Cl)[N+]([O-])=O)C1C=CC(=CC=1)N(C)CVinblastine is a natural alkaloid isolated from the plant Vinca rosea Linn. Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the M phase of the cell cycle. This agent may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin dependent Ca++ transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis.