Phenoxodiol - CAS# 81267-65-4 Size:10mg solid Smiles: CC1=CC(NC(=O)NCCN2CCC(O)(CC3C=CC=CC=3)CC2)=C2C=CC=CC2=N1

Smiles: CC1=CC(NC(=O)NCCN2CCC(O)(CC3C=CC=CC=3)CC2)=C2C=CC=CC2=N1

LW6 affects the stability of the HIF-1α protein

3'-pyrrolidine]-5'-carboxamide

resulting in induction of cell differentiation

which inhibits tyrosine phosphorylation of VEGFR-2 (IC50 = 1

Phenoxodiol - CAS# 81267-65-4 Size:10mg solid Smiles: CC1=CC(NC(=O)NCCN2CCC(O)(CC3C=CC=CC=3)CC2)=C2C=CC=CC2=N1Phenoxodiol, a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas mediated apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1 S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner. Product information CAS Number: 81267 65 4 Molecular