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(3-chlorophenyl)[3
The NADPH Oxidase Family and Its Inhibitors
PubMed PMID: 26522013
immunoblotting of protein lysates from C33A-2D2 cells stimulated with SJ000291942 at different times is performed
Chemical Name: 4-(4-((dimethylamino)methyl)-2
JHU 37160 - CAS# 2369979-68-8 60202 (3-chlorophenyl)[3JHU 37160, CAS No. 2369979 68 8, is a high affinity and highly potent activator of hM3Dq and hM4Di DREADDs. It displays approximately 25 fold higher affinity for hM4Di compared to DREADD agonist 21. It selectively displaces [3H]clozapine from DREADDs in vivo, but not from other clozapine binding sites. JHU 37160 inhibits locomotor activity in mice expressing hM3Dq and hM4Di in D1 expressing neurons, and increases hM3Dq stimulated locomotion in rats
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