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as an immunosuppressive drug
suppresses caspase 3 activity and recovers p38 MAPKγ expression in the retina after NMDA-induced injury
Low-dose GP531 reduces infarct size by 34% compared with vehicle and reduces the extent of the anatomic no-reflow zone by 31% compared with vehicle
4-diazepan-1-yl)-N-[(5-methylpyrazin-2-yl)methyl]-8-oxo-11-thia-1
2 nM in the β-arrestin and Ca2+ release assay
ACT 178882 Catalog No.:M23965-C as an immunosuppressive drugACT 178882 is a new Renin inhibitor with an IC50 of 1. 4 nM. Product information CAS Number: 1007392 69 9 Molecular Weight: 647. 03 Formula: C33H38Cl3N3O4 Chemical Name: (3R,4S) N {[2 chloro 5 (2 methoxyethyl)phenyl]methyl} N cyclopropyl 4 {6 [2 (2,6 dichloro 4 methylphenoxy)ethoxy]pyridin 3 yl}piperidine 3 carboxamide Smiles: CC1C=C(Cl)C(OCCOC2=CC=C(C=N2)[C@H]2CCNC[C@@H]2C(=O)N(CC2=CC(CCOC)=CC=C2Cl)C2CC2)=C(Cl)C=1 InChiKey: PGSRKJVMAOWDEC SXOMAYOGSA