TCO-PEG3-TCO Catalog No.:M13234-2 GSK-25 has promising oral bioavailability

GSK-25 has promising oral bioavailability (49% in male Sprague-Dawley rats and 19% in monkey)

Smiles: OC(=O)C1=CC=CN=C1NC1=CC(=CC=C1)C(F)(F)F

1-3H3/b11-6+

aslo known as IT-139 and KP-1339

2016 Sep 17

TCO-PEG3-TCO Catalog No.:M13234-2 GSK-25 has promising oral bioavailabilityTCO PEG3 TCO is a PEG based PROTAC linker can be used in the synthesis of PROTACs. Product information CAS Number: 2243569 22 2 Molecular Weight: 496. 64 Formula: C26H44N2O7 Chemical Name: (4Z) cyclooct 4 en 1 yl N [2 (2 {2 [2 ({[(4Z) cyclooct 4 en 1 yloxy]carbonyl}amino)ethoxy]ethoxy}ethoxy)ethyl]carbamate Smiles: O=C(NCCOCCOCCOCCNC(=O)OC1CCC=CCCC1)OC1CCC=CCCC1 c: 21,31 InChiKey: MPSXYJJDPFGIHW LEWNYYKSSA N InChi: InChI=1S C26H44N2O7 c29 25(34 23 11