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RWJ 67657 inhibits TNF-alpha production in lipopolysaccharide-injected mice (87% inhibition at 50 mg/kg) and in rats (91% inhibition at 25 mg/kg) after oral administration
which is statistically significant when compared to saline
WEHI-345 delays RIPK2 ubiquitylation and NF-κB activation downstream of NOD engagement
5-dimethyl-1H-imidazol-4-yl]ethynyl}pyridine
N-dimethylsemicarbazone
VH 032 amide-alkylC5-acid Size:10mg solid RWJ 67657 inhibits TNF-alpha productionFunctionalized von Hippel Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC5 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. Product information CAS Number: 2162120 87 6 Molecular Weight: 572. 72 Formula: C29H40N4O6S Synonym: VH 032 amide alkylC5 acid VH 032 amide alkylC5 acid VH 032 amide