L-Leucine-7-amido-4-methylcoumarin hydrochloride Catalog No.:M26568-C Abstract 836: ATR inhibitor BAY

Abstract 836: ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models

CAS Number: 139504-50-0

Smiles: CC1=CC=C(C=C1NC1=NC(=CC=N1)C1=CN=CC=C1)NC(=O)C1C=CC(CN2CCN(CC2)C(=O)COCCOCCOCCOC2=CC(=CC=C2)C(=O)C2=CSC(=N2)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](C)NC)C2CCCCC2)=CC=1

Smiles: N[C@@H](CN1C=C(I)C(=O)N(CC2C=CC(=CC=2)C(O)=O)C1=O)C(O)=O

Smiles: CC(OC(=O)NCCCN=[N+]=[N-])C1=CC(OC)=C(C=C1[N+]([O-])=O)OCCCC(=O)NCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

L-Leucine-7-amido-4-methylcoumarin hydrochloride Catalog No.:M26568-C Abstract 836: ATR inhibitor BAYL Leucine 7 amido 4 methylcoumarin (Leu AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L Leucine 7 amido 4 methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro. Product information CAS Number: 62480 44 8 Molecular Weight: 324. 80 Formula: C16H21ClN2O3 Chemical Name: (2S) 2 amino 4 methyl N (4 methyl 2 oxo 2H chromen 7 yl)pentanamide hydrochloride Smiles: