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Cholic acid competitively binds Na+/taurocholate cotransporting polypeptide (NTCP) on HepG2 cells and significantly inhibits the uptake of Cholic acid (CA)-nanoliposomes (LPs)-Doxorubicin (DOX)-HCl
CC1N=CSC=1C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCN)C(C)(C)C)C=C1
1 μM when measured in ion-leaky vesicles in the presence of 1 mM potassium
increased liver weight and cell proliferation
InChi: InChI=1S/C42H68O12/c1-9-29-21-33-13-17-35(51-33)25(5)39(43)47-24(4)20-32-12-16-38(50-32)28(8)42(46)54-30(10-2)22-34-14-18-36(52-34)26(6)40(44)48-23(3)19-31-11-15-37(49-31)27(7)41(45)53-29/h23-38H
UDM-001651 Size:Contact [email protected] for quotation Cholic acid competitively binds Na+/taurocholateUDM 001651 is a potent, selective, and orally bioavailable protease activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1. 4 nM). UDM 001651 shows antiplatelet potency (IC50=25 nM) in a thrombin induced platelet rich plasma aggregation assay ( Thr PRP). Product information CAS Number: 1477497 01 0 Molecular Weight: 513. 56 Formula: C28H23N3O5S Chemical Name: 6 (4 {[3 (benzyloxy)phenyl]methoxy} 6 methoxy 1 benzofuran 2 yl) 2 methoxyimidazo[2,1
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