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and potential for combination in preclinical models
(E)-N-(2-aminophenyl)-3-(1-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)sulfonyl)-1H-pyrrol-3-yl)acrylamide 4-methylbenzenesulfonate
(2004) Cell
It inhibits class I HDAC with IC50 of 1
ITD-1 promoted cardiomyocyte differentiation specifically via degradation of the TGFβ type II receptor (TGFBR2)
Forskolin - Adenylyl Cyclase Activator. CAS# 66428-89-5 60321 and potential for combination inForskolin, CAS No. 66428 89 5, is a small molecule activator of adenylate cyclase (EC50~5 10 M) in a rapid and reversible manner, to increase the intracellular levels of cAMP. Forskolin is used in many stem cell differentiation conditions, such as potentiating neuronal differentiation. Product information CAS Number: 66428 89 5 Molecular Weight: 410. 50 Formula: C22H34O7 Chemical Name: (3R,4aR,5S,6S,6aS,10S,10aR,10bS) 6,10,10b trihydroxy 3,4a,7,7,10a