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BACE-IN-1 (Compound 13) is a substituted lmidazo[1
with no significant weight loss occurring after chronic ND-646 dosing
Smiles: OC([C@H](O)CO)[C@H](O)CO
Chemical Name: 5-phenyl-[1
The living RAW264
type II collagen fragment Catalog No.:M23465-C BACE-IN-1 (Compound 13) is aType II collagen is composed of a triple helix of three identical chains. These molecules associate to form a fibril that is stabilized by intermolecular crosslinks1. Damage to the fibrillar meshwork, made up of primarily type II collagen (z 9095%), may be a critical event in the pathology of many arthritides, due in part to the very slow rate of collagen turnover within the cartilage2. Type II collagen and aggrecan (a large, aggregating proteoglycan)
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