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MK-447 (20 and 50 mg/kg
with a potency greater than that of other carbapenem antibiotics
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6-Hydroxyazepan-2-one alacic acid MK-447 (20 and 50 mg/kgIsavuconazole (BAL4815; trade name Cresemba) is a triazole antifungal drug. Its prodrug, isavuconazonium sulfate (BAL8557), was granted approval by the U. S. Food and Drug Administration (FDA) on March 6, 2015. Isavuconazole has been approved for treatment of invasive aspergillosis and invasive mucormycosis in adults ages 18 years and older. Both infections are caused by mold and fungi common to the environment, and occur in individuals who are