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13(5):513-22
94 μM and 2
Grobelny D
It first became available in Europe in 1984
SB-743921 (2 nM) in combination with imatinib displays additive anti-proliferative effect in KCL22 and CML CD34 + cells
NVP-QAV680 lu-Pro-Phe-Ome 13(5):513-22NVP QAV 680 is a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases. A highly selective compound, it has low nM functional potency for inhibition of CRTh2 driven human eosinophil and Th2 lymphocyte activation in vitro. Product information CAS Number: 872365 16 7 Molecular Weight: 358. 41 Formula: C18H18N2O4S Synonym: QAV 690 free acid NVP QAV 680 Chemical Name: 2 {1 [(4 methanesulfonylphenyl)methyl] 2