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6-dimethyloxan-2-yl]-3-methylpenta-1
4-oxadiazol-3-yl]pyridine hydrochloride
AG-490 at 30 μM inhibits not only Epo-induced phosphorylation of wild-type JAK2 but also constitutive phosphorylation of the JAK2 V617F mutant
15S)-14-amino-2-(3-amino-3-oxopropyl)-5
Formula: C19H24N4O2S
TG4-155 62175 6-dimethyloxan-2-yl]-3-methylpenta-1TG4 155 is a potent, brain permeant and selective EP2 receptor antagonist with a Ki of 9. 9 nM. TG4 155 shows low nanomolar antagonist activity against only EP2 and DP1. TG4 155 has an EP2 Schild KB of 2. 4 nM and displays 550 4750 fold selectivity for EP2 over EP1, EP3, EP4 and IP, but only 14 fold selectivity against the DP1 receptor. Product information CAS Number: 1164462 05 8 Molecular Weight: 394. 46 Formula: C23H26N2O4 Chemical Name: (2E) N [2
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